Why should aspirin not be taken on an deserted stomach?
Answers: Aspirin can simply sit on the lining of the stomach, the gastric mucosa, and burn for a while ulcer crater into it, a so-called gastric peptic sore. The aspirin in the crater have been see on endoscopy.
From http://query.nytimes.com/gst/fullpage.ht... :
"A less ambiguous role is played by aspirin and other drugs within the family of nonsteroidal anti-inflammatory drugs, used extensively to treat arthritis. Dr. James F. Fries at Stanford University and others argue that ulcer caused by these drugs represent the most adjectives adverse effect of all these drugs."
From http://www.emedicine.com/med/topic849.ht...
"Since 1989, approximately 500,000 general public are estimated to be afflicted with gastric spot. The decline in gastric sore is in some bit attributable to the declining prevalence of H pylori. Although the rate of simple gastric spot is in decline, the incidence of complicated gastric swelling and hospitalization has remained stable, incompletely due to the concomitant use of aspirin in an aging population."
"A 2005 study showed that contained by patients with aspirin-induced carbuncle, contrary to popular belief, aspirin plus esomeprazole (Nexium) was superior to clopidogrel (Plavix) within preventing recurrent gastric carbuncle bleeding"
To protect the stomach, either aspirin should be taken near food, and/or a special enteric-coated aspirin should be taken:
From http://www.bmj.com/cgi/content/full/311/...
"Evidence indicates that enteric coated aspirin is not accompanied by the dignified risk of adverse effects found with plain aspirin or the much more expensive anti-inflammatory drugs"
it hurts?
can impose upset stomach?
even bleeding in the stomach facing?
In empty stomach mechanism our stomach has dilute acids resembling hcl inorder to digest some food . aspirin is 2acetooxybenzoic acid ie., its an bitter when acid mixes next to an acid here will high concentration of acerbic and causes rupture of stomach wall explicitly it causes spot .
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