What is ICAM. What is the function and why is it's even elevated contained by absolute diseases?
Answer:
The ICAM involved in the stable attachment of white blood cell to the endothelial cell in inflammation . is widely upregulated on tons cells including B or T lymphocytes, and endothelial cell during inflammation aiding cell entry to the infect site. It mediates immune and inflammatory responses and interaction of white blood cell and target cells to recognise foreign proteins eg germs virus, damage. It is big in the adhesion of cell to activated endothelium ( bin liner on blood vesses). The amount of expression can be induced several fold by inflammatory molecules secreted from other ells. look up icam on web
InterCellular Adhesion Molecules.
ICAM-1 is overexpressed surrounded by inflammatory states.