Does methadone exact other drugs to stay contained by your system longer, so that a drug trial would not be correct?
Answers: sorry to be the bearer of bad communication, but that's not true. The half-life of cocaine is about 72 hours, regardless of anything opiates he's doing. It may stay in his system slightly longer if he did a LOT of it, but a month is still much too long to be plausible.
Here's a connect that explains it a little:
http://www.druglibrary.org/schaffer/coca...
In lay down for that to be true, methadone and cocaine would have to be metabolized by alike pathway, and they are not. Methadone is broken down by a certain enzyme, but it is not indistinguishable one that breaks down cocaine. (if cocaine was broken down by indistinguishable enzyme, it would be listed on the "substrates" table on the knit below) There are some drugs known to inhibit the breakdown of others, and these are planned under the "inhibitor" table at the relationship below. However, cocaine is NOT broken down by this enzyme system, and will be unaffected within any case.
http://medicine.iupui.edu/flockhart/clin...
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