Why are the dosages for positive drugs given to epileptic patients different for females and males?
Answers: The above answerer is broadly correct, of course, but I regard as the answer you are looking for is more distinct.
Most anti-epileptic drugs are "enzyme inducers". What we mean by this is that they tend to up-regulate the liver's 'detoxification enzymes' (specifically, elements of the cytochrome P450 family). The liver thus metabolises these more at full tilt.
Now, what happens if you afford this patient a different drug? Well, if it is not usually detoxified by the enzymes that hold now be up-regulated, nothing much change. However, if it happens to depend on one and the same set of enzymes that the anti-epileptics do, things get interesting. Since the enzymes enjoy been switched to a 'more powerful' state, they will metabolise the unusual drug more quickly, and so its level in the body will be lower than they otherwise would hold been.
To compensate for this, the doses of guaranteed medications enjoy to be increased in patients on treatment for epilepsy.
Hope that help!
They are in reality different in respectively individual patient.
This is because they interact differently within each lenient according the the patient's body weight, requisition threshold, fat stores, medication and hepatic metabolism.
Dosage is by body weight, not sexual category. Every patient and every drug is different. Some drugs induce enzymes that verbs other drugs. So the doctor starts with what should be the proper dose according to solidity , and adjusts.
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