Why acetylcholine isn't used as a drug??
Answers: It actually IS used as a drug, for vasodilation. See the insinuation for an article describing the response of pulmonary circulation to acetylcholine in patients near primary pulmonary hypertension.
It isn't widely used partly because, as a inherently occurring neurotransmitter, the body has the way to break it down quickly, so its effect is short lived.
How would you obtain it to the target organ? Overhelm the body's entire cholinesterase system? And if you did, it's no fun treating those people.
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