Do Aspirin 75mg (used to prevent strokes) tablets interact beside any other medicine.?
Answers: Drug Interactions
Substrate of CYP2C8/9 (minor)
ACE inhibitors: The effects of ACE inhibitors may be blunted by aspirin administration, mainly at higher dosages.
Buspirone increases aspirin's free % surrounded by vitro .
Carbonic anhydrase inhibitors and corticosteroids have be associated with alteration contained by salicylate serum concentrations.
Heparin and low molecular weight heparins: Concurrent use may increase the risk of bleeding.
Methotrexate serum level may be increased; consider discontinuing aspirin 2-3 days before high-dose methotrexate treatment or avoid concurrent use.
NSAIDs may increase the risk of gastrointestinal adverse effects and bleeding. Serum concentrations of some NSAIDs may be decrease by aspirin.
Platelet inhibitors (IIb/IIIa antagonists): Risk of bleeding may be increased.
Probenecid effects may be antagonized by aspirin.
Sulfonylureas: The effects of older sulfonylurea agents (tolazamide, tolbutamide) may be potentiated due to displacement from plasma proteins. This effect does not appear to be clinically significant for newer sulfonylurea agents (glyburide, glipizide, glimepiride).
Valproic acerbic may be displaced from its binding sites which can result in toxicity.
Verapamil may potentiate the prolongation of bleeding time associated beside aspirin.
Warfarin and oral anticoagulants may increase the risk of bleeding.
Ethanol/Nutrition/Herb Interactions
Ethanol: Avoid ethanol (may enhance gastric mucosal damage).
Food: Food may decrease the rate but not the extent of oral digestion.
Folic acid: Hyperexcretion of folate; folic sour deficiency may result, prime to macrocytic anemia.
Iron: With chronic aspirin use and at doses of 3-4 g/day, iron-deficiency anemia may result.
Sodium: Hypernatremia resulting from buffered aspirin solutions or sodium salicylate containing high sodium content. Avoid or use beside caution surrounded by CHF or any condition where hypernatremia would be detrimental.
Benedictine liqueur, prunes, raisins, tea, and gherkins: Potential salicylate throng.
Fresh fruits containing vitamin C: Displace drug from binding sites, resulting in increased urinary excretion of aspirin.
Herb/Nutraceutical: Avoid cat's claw, dong quai, evening primrose, feverfew, garlic, ginger, ginkgo, red clover, horse chestnut, green tea, ginseng (all enjoy additional antiplatelet activity). Limit curry powder, paprika, licorice; may effect salicylate accumulation. These foods contain 6 mg salicylate/100 g. An ordinarily American diet contains 10-200 mg/day of salicylate.
it doesnt, but also it is proven flase in the region of preventing strokes!
learn ur prescription man~
Yes- NSAIDs like Ibuprofen and Diclofenac. This is a chancy combination, and can cause internal bleeding. As for any others, you'd hold to ask your pharmacist.
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