What do the abbreviation SERT, NET, DAT connote when speaking of depression?
Answers: SERT = serotonin transporter
NET = norepinephrine transporter
DAT = dopamine transporter
All of these are proteins that are part of the neuronal cell membrane, and they function to remove serotonin, norephinephrine or dopamine, respectively, from the synaptic cleft. By inhibiting these proteins, more of the transmitter stays within the cleft for longer periods of time. Hope this answers your examine.
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