I mean why is it better to purloin statins before bedtime (at evening) than at morning. F.e. the h2-blockers are taken at evening because more hystamin is secreted at darkness so the effect of the drug will be better. So what effect of the statins will be better if they r taken at night?
Answer:
The plea that the earlier available statins be recommended for use at night be because they had relatively short partly lives, and bedtime administration worked best because surrounded by most people cholesterol biosynthesis take place in the untimely morning hours.
However that is not the defence with Lipitor, Crestor or Pravachol, since they enjoy half lives of 19-22 hours and accordingly morning admiistration would be more suitable.
Other factors include once a daytime doses that might or do cause drowsiness to be taken at darkness, or drugs that react near foods to be taken when one is not going to be eating, such as bed time.
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