Metformin side effects?
Answers: Dear Hotmetal,
The most adjectives adverse effect of metformin is gastrointestinal upset, including diarrhea, cramps, nausea and vomiting; metformin is more commonly associated with gastrointestinal side effects than most other anti-diabetic drugs.
In a clinical trial of 286 subjects, 53.2% of the 141 who be given immediate-release metformin (as opposed to placebo) reported diarrhea, versus 11.7% for placebo, and 25.5% reported nausea/vomiting, versus 8.3% for those on placebo.
Gastrointestinal upset can grounds severe discomfort for patients; it is most common when metformin is first administered, or when the dose is increased. The discomfort can recurrently be avoided by beginning at a low dose (1 to 1.7 grams per day) and increasing the dose at a snail`s pace.
MOST IMPORTANTLY:
Gastrointestinal upset after prolonged, steady use is less adjectives.
So a gradually increasing dose help.
It is also interesting to note that Metformin can rationale Vit B12 defeciency---this is a gastro-intestinal affect, but not related to your abdominal cramps.
Hope this helps
Rehman
I have exact same side effects in second week on Metformin after tally evening dose. It felt close to cholecystitis (gall bladder attack) and kept getting worse for 5 days over New Years. When my doctor got put money on from vacation, she said to stop the medication. I did, and the cramp gradually subsided, but it took four days for it to walk away and still recurs occasionally. Keep well thought-out records of symptoms and blood glucose meter reading, and consult your endocrinologist as soon as you can get an appointment. Also, drink lots of sea and avoid fried & fatty food.
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