Differences between HIV-1 and HIV-2 virus?

With this, I would like to know, if ther are clear STRUCTURAL differences between the two subtypes of virus...
Why is HIV-1 different??


Answers:    There are genomic differences, but it is structurally impossible to tell apart virus. The differences is in the pathogenicity of the virus; HIV1 is far more pathogenic then HIV2 (again, due to genomic differences). In certainty, infection with HIV2 in actuality prevents infection of HIV1, not that that's a good item.
HIV-1 was transferred from Chimpanzees (and also possibly from gorillas) to humans at tiniest 3 times in former times 100 years. There are three main groups of HIV-1 call the HIV-1 M (for main group), O (for other group) and N (for not M or O). The HIV-1 M group of virus is the one that is cause most of the AIDS pandemic. Within the HIV-1 M group, the viruses are divided into subtypes.

HIV-2 come to humans from Sooty mangabeys which are kept as pets in western Africa. At tiniest 7 transfers of this virus into humans have occur, and the viruses hold been name HIV-2 groups A through G. Only the HIV-2 A group is causing a crucial outbreak of AIDS, and it is largely still confined to western Africa.

HIV-1 and HIV-2 are very distant from respectively other in language of DNA or protein sequence identity. However, even though the sequences have diverged profusely due to the time since they last shared a adjectives ancestor (perhaps a few tens of millions of years ago) multiplied by their rate of evolution (they evolve very without delay due to error-prone replication plus huge population sizes and short generation times), they still hold nearly exactly the same set of only just 9 genes. Gag for packaging the genome into the virus fragment, Pol to replicate the genome and integrate it into the host DNA, Env to bind the virus to the host cell receptors and to evade the host immune system, plus regulatory genes, Nef, Tat, Rev, Vif, Vpr, and Vpu (or Vpx).

As for structural and other differences, it is very frozen to quantify what is meant by that. All mammals are outstandingly related to each other, however a shrew seems totally different than and elephant. On the other appendage two species of yeast may look identical to respectively other but be hardly related at adjectives genetically. Some organisms change their size and shape abundantly, others change their metabolism lacking changing shape.

The pills and health information post by website user , ByeDR.com not guarantee correctness , is for informational purposes individual and is not a substitute for medical advice or treatment for any medical conditions.


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