Do digestive enzymes affect the break down and release of extended release meds? PLease HELP?
I have even contacted several of the manufacturers of the enzymes with no response. Does anyone know for sure, or can someone point me to research on this topic. Can't seem to find info online. Thanks sooooooooo much!!
Answer:
The answer is that they could both be right.
There are some pills with a coating on them. that cannot be dissolved within the stomach and are instead released when in the small intestines. This is because the drug itself would not likely survive the acid bath in the stomach and needs to be in a less volatile environment to pass into your blood stream.
Typically though, these are not XR formluations.
Typically XR formulations are going to either be catatonic or anionic meaning that they are broken down through the rate at which various salts are metabolized in your body. This is what the pharmacist meant by being related to their pH levels.
As the various types of salt (HCL's for anionic / K's for catatonic) are broken down and metabolized, the drug is released from the binding resin (salts).
Or something like that, it gets a little fuzzy when you dig deeper than that... Either way, enzymes shouldn't be a problem because they're working on much larger level molecules at that point anyways.